Uterine fibroids(Leiomyomas ) Leiomyomas are benign smooth muscle neoplasms that typically originate from the myometrium. They are often referred to as uterine myoma Causes 1.Estrogen Effects -Uterine leiomyomas are estrogen- and progesterone-sensitive tumors .Consequently, they develop during the reproductive years. After menopause, leiomyomas generally shrink, and new tumor development is infrequent. Leiomyomas themselves create a